A scientific literature network is created using human curated CAS indexing information. This tool enables the exploration of the co-occurrence network of protein targets of interest, drug-like substances, and antiviral activity within a unique document set related to COVID-19. Starting with the CAS COVID-19 Protein Target Thesaurus, you can navigate through a collection of CAS curated documents found to be relevant to antiviral compounds. Bidirectional relationships between the protein targets and candidate antiviral substances are established with predicted high, medium, and low strength associations in corresponding documents.

COVID-19 Target List

Target NameDocumentsSubstances
RNA-dependent RNA polymerase928100,703
RNA-dependent RNA polymerase NS5B74539,708
Dipeptidyl peptidase IV12119,239
Interleukin 6 receptors5011,121
Microsomal aminopeptidase368,556
Nucleocapsid proteins1286,964
Dihydroorotate oxidase393,930
Immunoglobulin receptors493,515
Angiotensin AT1 receptors203,299
Cathepsin B872,794
Viral nonstructural protein NS2812,644
Proteinase 3CLpro1322,482
Clathrin adaptor proteins112,436
Viral nonstructural protein NS4362,383
Interleukin 1 receptors412,368
Viral matrix M proteins352,193
Viral spike glycoproteins1232,063
Interferon-induced transmembrane protein 3201,191
Viral nonstructural protein NS11131,035
Cathepsin L461,015
Interferon-induced transmembrane protein 121934
Proteinase Furin51893
C-type lectin CLEC4M1883
Viral nonstructural protein NSp720640
Cyclin G-associated kinase14586
Interleukin 8 receptors11498
Niemann-Pick C1 protein13497
Angiotensin-converting enzyme 258478
Proteinase PLpro19277
Transmembrane serine proteinase 214239
Angiotensin AT2 receptors4191
Caveolin 15120
Dynamin 24119
Karyopherin β592
Karyopherin α678
Protein serine/threonine kinase AAK1556
Minor nucleoprotein VP30110
Interferon-induced transmembrane protein 2510